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Jan-Christian Wasmuth and Jurgen Rockstroh

HIV and HCV Coinfections

Coinfection with HIV and HCV occurs frequently, due to the fact that both are transmitted via the same pathways (parenteral, sexual, vertical). 240,000 people (30% of HIV-infected individuals) are estimated to be infected with both viruses in the USA.

Several European countries have even higher rates of coinfection. In Spain, at least 50% of the 130,000 HIV-infected patients are also HCV-positive as a result of the high incidence of i.v. drug users. More than 90% of coinfected individuals are positive for HCV RNA, i.e. have chronic hepatitis C.

HIV and HBV Coinfections

The hepatitis B virus is one of the most common human pathogens worldwide. Up to 95% of all HIV-infected patients have been infected with hepatitis B, and approximately 10-15% have chronic hepatitis B, with considerable variation among geographical regions and risk groups. It is estimated that around 100,000 HIV-infected patients in the USA suffer from chronic hepatitis B. Sexual transmission is the most frequent route of contraction. more...